12.11.2010

drug downside

Imagine if your infant or toddler had to deal with the following drug side effects, in this case from Clobazam, the benzodiazepine that Calvin has to take:

Drowsiness, dizziness, tiredness, fatigue, loss of coordination, constipation, loss of appetite, muscle weakness, dry mouth, tremor, weight gain, restlessness, rapid/pounding/irregular heartbeat, changes in vision, slurred speech, confusion, depression, irritability, behavioral changes, rash, itching, swelling, severe dizziness, trouble breathing.

Physical and psychological dependence are known to occur in persons taking benzodiazepines.

Anterograde amnesia (inability to remember new information) is known to occur after administration of benzodiazepines.

Contra-Indications include hypersensitivity to clobazam, severe muscle weakness (myasthenia gravis) and narrow-angle glaucoma.

Withdrawal symptoms have been observed after abrupt discontinuation of benzodiazepines. These include seizures, irritability, nervousness, insomnia, agitation, tremors, diarrhea, abdominal cramps, vomiting and mental impairment.

Loss of part or all of the anticonvulsant effectiveness of clobazam has been described in patients who have been receiving the drug for some time.

Excitement and other paradoxical reactions can result from the use of benzodiazepines.

In patients for whom prolonged therapy with clobazam is indicated, blood counts and liver function should be monitored periodically.

These are just a few reasons why we need to find a cure.


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